News

Kidney International® 

A nationwide register-based cohort study examined the association between preeclampsia in mothers and the risk of kidney disease in their offspring 

A large cohort study of over 2.2 million births has found that children born at term to mothers with preeclampsia face a higher risk of developing kidney disease later in life. 

The study revealed increased rates of several types of kidney conditions, particularly after the age of 25. These associations persisted even after accounting for preterm birth, suggesting that preeclampsia itself may have a direct, long-term impact on kidney health in offspring.  

The findings highlight the importance of incorporating kidney monitoring into postpartum preeclampsia follow-up care. 

Kidney International Reports® 

Safety of drugs in breastfeeding women with CKD 

Women with chronic kidney disease (CKD) often lack clear evidence-based guidance on medication safety during breastfeeding, leading some to stop treatment or forgo breastfeeding altogether. 

In a review of 81 studies, researchers assessed the safety of commonly prescribed CKD medication during lactation using data from PubMed®, REPROTOX®, and LactMed®. 

Several drugs, including enalapril, captopril, tacrolimus, and azathioprine, were considered compatible with breastfeeding. However, data on newer agents, such as SGLT2 inhibitors, GLP-1 receptor agonists, and complement inhibitors, remain limited, warranting cautious use until further evidence becomes available.