Journals

ISN Journal summaries on gender-specific kidney health and ethical considerations in CKDu research 

Kidney International®   Women and kidney health: Conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference The conference highlighted key sex- and gender-specific issues in kidney care, emphasizing chronic kidney disease’s (CKD) impact on women’s reproductive health and pregnancy outcomes.   Recommendations included counseling, multidisciplinary pregnancy management, and systematic monitoring of kidney function, blood pressure, and proteinuria.   The...

September 1, 2025Journals, NewsRead more...

ISN Journal summaries on MGRS risk prediction and CKD screening 

Kidney International®  The Mayo MGRS Prediction Tool calculates the risk of finding monoclonal gammopathy of renal significance in a kidney biopsy in patients with monoclonal gammopathy   Determining which patients with chronic kidney disease (CKD) and monoclonal gammopathy should undergo a kidney biopsy to diagnose monoclonal gammopathy of renal significance (MGRS) remains a clinical challenge.  Researchers developed and...

July 28, 2025Journals, NewsRead more...

ISN journal summaries on maternal preeclampsia and CKD medication safety during breastfeeding    

Kidney International®  A nationwide register-based cohort study examined the association between preeclampsia in mothers and the risk of kidney disease in their offspring  A large cohort study of over 2.2 million births has found that children born at term to mothers with preeclampsia face a higher risk of developing kidney disease later in life.  The study revealed...

July 14, 2025Advocacy, Journals, NewsRead more...

ISN Journal summaries on the SONG initiative and public data in research 

Kidney International®  The Standardized Outcomes in Nephrology (SONG) initiative: A decade of harmonizing patient voices and research in kidney disease   The authors of this editorial highlight how research on chronic kidney disease has been hindered by inconsistent and often patient-irrelevant reporting of outcomes.   This challenge prompted the launch of the global Standardized Outcomes in Nephrology (SONG) initiative...

June 30, 2025Journals, NewsRead more...

ISN Journal summaries on membranous nephropathy and disaster management

Kidney International® Designing clinical trials for the treatment of membranous nephropathy in the anti-PLA2R era: Results of a NephCure membranous nephropathy workshop Membranous nephropathy (MN) is a leading cause of adult nephrotic syndrome, and anti-PLA2R antibodies are now recognized as key biomarkers reflecting disease activity in many patients. At a 2023 NephCure workshop, experts discussed how to...

May 26, 2025Journals, NewsRead more...

ISN Journal summaries on nephrotic syndrome in children and obesity’s role in CKD 

Kidney International®  Executive summary of the KDIGO 2025 Clinical Practice Guideline for the Management of Nephrotic Syndrome in Children  The 2025 KDIGO executive summary updates guidance on managing nephrotic syndrome in children, introducing a treatment algorithm and aligning definitions with international standards.   It revises relapse prevention strategies, recommends against routine steroid use during infections, and emphasizes personalized...

May 12, 2025Journals, NewsRead more...

ISN Journal summaries on CONVINCE trial findings and kidney transplantation in Iran 

Kidney International®  A health economic evaluation of the multinational, randomized controlled CONVINCE trial: cost-utility of high-dose online hemodiafiltration compared to high-flux hemodialysis  Patients with kidney failure often receive either high-flux hemodialysis (HD) or high-dose hemodiafiltration (HDF). Previous research shows HDF may lower the risk of death compared to HD.   This study looked at whether the potential health...

April 28, 2025Journals, News, ResearchRead more...

KIR publishes on findings from the ISN Western Europe Regional Board survey on preferred meeting formats 

Kidney International Reports® (KIR) has published as an article-in-press the results of a survey conducted by the ISN Western Europe Regional Board on preferred scientific meeting formats— in-person, virtual, or hybrid.   Explore the survey findings in KIR   “Nephrology health professionals' perspectives on their preferred modality for scientific meetings, balancing affordability, sustainability and opportunities to interact...

April 7, 2025Journals, News, Regional Activities, ResearchRead more...

ISN Journal summaries on IgA nephropathy and conservative kidney management

Kidney International®  Treatment of patients with IgA nephropathy: a call for a new paradigm  Current treatments for IgA nephropathy (IgAN), including supportive care and corticosteroids, have limited success and significant side effects.   Advances in understanding IgAN’s pathogenesis have led to new targeted therapies and a proposed dual approach: targeting IgAN-specific mechanisms (e.g., pathogenic IgA production) and managing...

April 7, 2025Journals, NewsRead more...

ISN Journal summaries on CKD-MBD, Pexivas trial, in-center hemodialysis, and the ISN Collaborative Quality Framework on Dialysis 

Kidney International® (KI)  Chronic Kidney Disease–Mineral and Bone Disorder: Conclusions From a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference  The 2023 KDIGO conference confirmed that the 2017 guidelines on managing chronic kidney disease–mineral and bone disorder (CKD-MBD) remain valid but proposed reframing CKD-MBD around two clinical syndromes: CKD-associated osteoporosis and CKD-associated cardiovascular disease.  Future guidelines may...

March 24, 2025Journals, NewsRead more...

ISN Journal summaries on World Kidney Day  

Kidney International® (KI)  Are Your Kidneys OK? Detect Early to Protect Kidney Health  The  World Kidney Day (WKD) editorial in Kidney International highlights the importance of early kidney disease detection to protect kidney health, slow progression, and reduce cardiovascular risk. Simple tests — serum creatinine and urine albumin — enable early diagnosis, but barriers like funding...

March 10, 2025Journals, News, World Kidney DayRead more...

ISN Journal summaries on BK polyomavirus infection and the nurse’s role in managing symptoms of dialysis recipients

Insights from the BKEVER trial comparing everolimus versus mycophenolate mofetil for BK polyomavirus infection in kidney transplant recipients The BKEVER trial compared everolimus (EVR) with mycophenolate mofetil (MMF) in kidney transplant recipients with BK polyomavirus (BKPyV) infection to assess which strategy led to faster viral clearance. Results showed that reducing MMF was more effective, with 81.3%...

February 24, 2025Journals, NewsRead more...

ISN Journal Summaries on Clinical Practice Guideline for ADPKD and Mitochondrial Function in Diabetic Kidney Disease

Kidney International® KDIGO 2025 Clinical Practice Guideline for the Evaluation, Management, and Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD): Executive Summary The KDIGO 2025 Clinical Practice Guideline for ADPKD is the first global guideline on the evaluation, management, and treatment of this genetic disorder, focusing on areas such as diagnosis, kidney manifestations, disease progression, and extrarenal...

February 3, 2025Journals, NewsRead more...

Meet the KI-ISN Early-Career Researchers and ISN-KI Editorial Fellows!

The ISN-KI/KIR Editorial Fellows Session: The Best of 2024/25 Articles will take place at WCN’25 on Saturday, February 8, 2025, from 9:45-11:15 a.m.  KI-ISN Early-Career Researcher Awardees and ISN-KI Editorial Fellows will be honored during this session. KI-ISN Early-Career Researcher Awards honor exceptional basic and clinical science research published in Kidney International® (KI) in the...

February 3, 2025Awards, Journals, NewsRead more...

ISN Journal Summaries on Immunosuppression Treatments for Glomerular Disease and Blood Disorders With Kidney Involvement  

Kidney International® Evaluating the Risk of Cardiovascular Events Associated With Different Immunosuppression Treatments for Glomerular Diseases This study analyzed 1,912 adults with glomerular disease from Canada to evaluate the cardiovascular risks associated with immune therapies used for treatment. The findings reveal that prolonged exposure to calcineurin inhibitors and cyclophosphamide is linked to a higher risk of...

January 21, 2025Journals, NewsRead more...

ISN Journal Summaries on Hypertension-avoidance Strategies and Age-based GFR    

Kidney International®  A Sub-study of the POISE-3 Randomized Trial Examined Effects of a Perioperative Hypotension-avoidance Strategy Versus a Hypertension-avoidance Strategy on the Risk of Acute Kidney Injury  This sub-study of the POISE-3 trial investigated whether a strategy to prevent low blood pressure during surgery could reduce the risk of acute kidney injury (AKI).   Researchers randomized 7,307 patients...

January 6, 2025Journals, News, ResearchRead more...

Celebrating ISN’s 2024 Publications: Driving Kidney Research for Better Patient Outcomes 

As we step into 2025, we reflect on the impactful ISN-led research of 2024. These studies deepen our understanding of kidney health and advance global kidney care as a health priority. Below, we highlight some of the year’s key contributions:    An Update on the Global Disparities in Kidney Disease Burden and Care Across World Countries...

January 6, 2025Journals, News, ResearchRead more...

ISN Journal Editorial Selections on aHUS Management, Rituximab Therapy, Methylmalonic Acidemia, and Rare Kidney Diseases

Kidney International® Outcomes From the International Society of Nephrology Hemolytic Uraemic Syndromes International Forum  The 2023 ISN aHUS Forum brought together global experts to discuss key challenges in managing complement-mediated hemolytic uraemic syndromes (HUS), including nomenclature, biomarkers, and treatment protocols. Key areas for future research were identified, such as genetic predisposition, optimal complement inhibitor use, and improving...

December 9, 2024Journals, ResearchRead more...

New Perspectives on Treatment Protocols: Kidney International® Publishes Late-breaking Clinical Trials

Two significant research studies were accepted as late-breaking clinical trials at Kidney Week 2024 and have subsequently been published in Kidney International®. Higher Intraoperative Blood Pressure Does Not Reduce Acute Kidney Injury in Non-Cardiac Surgery: What Do the Results of the POISE-3 Trial Tell Us?   The POISE-3 trial's analysis found no benefit in targeting a...

November 26, 2024Journals, News, ResearchRead more...