The mystery of chronic kidney disease of unknown origin (CKDu) continues to puzzle researchers, but efforts to solve it are gaining ground. The i3C Network is steadily expanding, bringing together researchers, clinicians, and public health experts with one shared goal: to uncover the causes behind CKDu and protect vulnerable populations. In July, over 40 experts...
From global policy tools to community-driven projects and early-career development, ISN's research initiatives offer meaningful opportunities for all professionals committed to advancing kidney care. Whether you're just starting out or looking to broaden your impact, you can grow, collaborate, and drive real impact through ISN-supported research activities. We invited several contributors to share what...
ISN-ACT Global Trials Focus editorial team member Michele Provenzano summarizes the design and outcomes of the latest "Trial of the month" featured in ISN-ACT Global Trials Focus. Trial of the month: DAPA-tolvaptan: First trial of SGLT2 inhibition in ADPKD with background tolvaptan therapy Open-label, randomized, controlled, crossover trial on the effect of dapagliflozin in patients with ADPKD receiving tolvaptan Uchiyama...
Why do millions of people worldwide still face limited access to dialysis despite advances in kidney care? This urgent question was at the heart of the recent ISN-GKHA webinar: “Global variations in hemodialysis access and outcomes – insights for improving kidney care worldwide,” based on two extensive global studies informed by 2023 ISN-Global Kidney Health...
Kidney International® Identifying strategies for disseminating research to patients with chronic kidney disease and caregivers: a workshop report Research on chronic kidney disease (CKD) is often inaccessible to patients and caregivers, limiting its influence on care and decision-making. A workshop involving patients, caregivers, and health professionals identified three key strategies to improve dissemination: making research engaging and...
Through robust data collection, international collaboration, and practical insights, the 2023 ISN-Global Kidney Health Atlas (ISN-GKHA) continues to drive progress in kidney care worldwide. This essential resource maps the availability and quality of kidney health services globally, helping kidney care professionals shape policy, support advocacy, guide research priorities, and identify service gaps, all toward...
Watch the video for an animated explanation of the study based on the visual abstract. These resources were supported by Vera Therapeutics
Kidney International® A health economic evaluation of the multinational, randomized controlled CONVINCE trial: cost-utility of high-dose online hemodiafiltration compared to high-flux hemodialysis Patients with kidney failure often receive either high-flux hemodialysis (HD) or high-dose hemodiafiltration (HDF). Previous research shows HDF may lower the risk of death compared to HD. This study looked at whether the potential health...
Kidney International Reports® (KIR) has published as an article-in-press the results of a survey conducted by the ISN Western Europe Regional Board on preferred scientific meeting formats— in-person, virtual, or hybrid. Explore the survey findings in KIR “Nephrology health professionals' perspectives on their preferred modality for scientific meetings, balancing affordability, sustainability and opportunities to interact...
PLOS Global Public Health recently hosted a roundtable with the lead authors of ISN-Global Kidney Health Atlas (ISN-GKHA) articles they published earlier this year. The authors highlight key insights from their research, which examined disparities in the availability, affordability, quality, and access to kidney care services across countries categorized by World Bank income group classifications. Watch...
The ISN-ACT Toolkit now features a section on Standard Operating Procedures (SOPs) in clinical trials to help improve clarity, consistency, and traceability in clinical trial processes. Access the SOP section of the ISN Clinical Trials Toolkit here Contributed by ISN-Advancing Clinical Trials Committee member Paula Andrea Marioli (Argentina) and colleagues, the section includes: Suggested SOP format – a structured guide...
ISN-ACT Global Trials Focus editorial team member Neeru Agarwal summarizes the design and outcomes of the latest "Trial of the Month" featured in ISN-ACT Global Trials Focus. Trial of the Month: Effect of muscle stretching and isometric exercises on quality of life in children undergoing regular hemodialysis Khalf-Allah et al., Pediatric Nephrology. 2024 39:3289-3299. Summary In this single-center study, 68...
Launched at WCN’25, the ISN-Global Kidney Health Atlas (ISN-GKHA) interactive map is a powerful visual tool to explore comprehensive global kidney health data from the 2019 and 2023 ISN-GKHA reports. This interactive, searchable platform highlights key trends currently shaping kidney health and care with the potential to drive improvements worldwide. Explore global kidney health...
PLOS Global Public Health recently published a series of articles using data from the third edition of the ISN-Global Kidney Health Atlas (ISN-GKHA), exploring gaps in availability, affordability, quality, and access to kidney care services across countries by World Bank income group classifications. Read the individual papers in PLOS Global Public Health: “Landscape of kidney replacement...
PLOS Global Public Health recently published a series of articles using data from the third edition of the ISN-Global Kidney Health Atlas (ISN-GKHA), exploring gaps in availability, affordability, quality, and access to kidney care services across countries by World Bank income group classifications. Read the individual papers in PLOS Global Public Health: “Landscape of Kidney Replacement...
The “ISN Global Kidney Trials Insights: A Guide for Everyone,” inspired by the ISN-ACT Global Trials Focus summaries, translates complex trial findings into accessible information. This initiative empowers people living with kidney disease and their caregivers to better understand advancements in kidney care. Access all the simplified summaries here. The latest case study features the SMART...
Kidney International® A Sub-study of the POISE-3 Randomized Trial Examined Effects of a Perioperative Hypotension-avoidance Strategy Versus a Hypertension-avoidance Strategy on the Risk of Acute Kidney Injury This sub-study of the POISE-3 trial investigated whether a strategy to prevent low blood pressure during surgery could reduce the risk of acute kidney injury (AKI). Researchers randomized 7,307 patients...
As we step into 2025, we reflect on the impactful ISN-led research of 2024. These studies deepen our understanding of kidney health and advance global kidney care as a health priority. Below, we highlight some of the year’s key contributions: An Update on the Global Disparities in Kidney Disease Burden and Care Across World Countries...
Watch the video here This video abstract was supported by Vera Therapeutics
The clinical trials workshop will be held on February 5, 2025, at the Pride Plaza Aerocity in New Delhi, India, as lead-up to the ISN World Congress of Nephrology 2025 (WCN’25) from February 6-9, 2025. It is organized by the ISN-ANIO committee, a collaboration between the ISN and the American Nephrologists of Indian Origin...
